VIRUSMYTH HOMEPAGE




PROTEASE INHIBITOR (SIDE) EFFECTS


Invirase (Hoffmann-LaRoche)

Body as a whole: allergic reaction, chest pain, edema, fever, intoxication, parasites external, retrosternal pain, shivering, wasting syndrome, weight decrease.

Cardiovascular: Cyanosis, heart murmur, heart valve disorder, hypertension, hypotension, syncope, vein distended.

Endocrine/Metabolic: Dehydration, dry eye syndrome, hyperglycemia, weight increase, xerophthalmia.

Gastrointestinal: Cheilitis, constipation, dysphagia, eructation, feces bloodstained, feces discolorred, gastralgia, gastritis, gastrointestinal inflammation, gingivitis, glossitis, hemorrhage rectum, hemorrhoids, hepatomegaly, melena, pain pelvic, painful defecation, pancreatitis, parotic disorder, salivary glands disorder, stomatitis, tooth disorder, vomiting.

Hematlogic: Anemia, microhemorrhages, pancytopenia, splenomegaly, thrombocytopenia.

Musculoskeletal: Arthralgia, arthritis, back pain, cramps muscle, musculoskeletal disorders, stiffness, tissue changes, trauma.

Neurological: Ataxia, bowel movements frequent, confusion, convulsions, dysarthria, dysesthesia, heart rate disorder, hyperesthesia, hyperreflexia, hyporeflexia, mouth dry, numbness face, pain facial, paresis, poliomyelitis, progressive multifocal leukoencephalopathy, spasms, tremor.

Psychological: Agitation, amnesia, anxiety, depression, dream excessive, euphoria, hallucination, insomnia, intellectual ability reduced, irritability, lethargy, libido disorder, overdose effect, psychotic disorder, somnolence, speech disorder.

Reproductive System: Prostate enlarged, vaginal discharge.

Resistance Mechanism: Abscess, angina tonsillaris, candidiasis, hepatitis, herpes simplex, herpes zoster, infection bacterial, infection mycotic, infection staphylococcal, influenza, lymphadenopathy, tumor.

Respiratory: Bronchitis, cough, dyspnea, epistaxis, hemoptysis, laryngitis, pharyngitis, pneumonia, respiratory disorder, rhinitis, sinusitis, upper respiratory tract infection.

Skin and Appendages: Acne, dermatitis, dermatitis seborrheic, eczema, erythema, folliculitis, furunculosis, hair changes, hot flushes, photosensitivity reaction, pigment changes skin, rash maculopapular, skin disorder, skin nodule, skin ulceration, sweating increased, urticaria, verruca, xeroderma.

Special Senses: Blepharitis, earache, ear pressure, eye irritation, hearing decreased, otitis, taste alteration, tinnitus, visual disturbance.

Urinary system: Micturition disorder, urinary tract infection.


Crixivan (Merck, Sharp & Dohme)

Body As A Whole/Site Unspecified: Abdominal distention, chest pain, chills, fever, flank pain, flu-like illness, fungal infeciton, malaise, pain, syncope.

Cardiovascular System: Cardiovascular disorder, palpitation.

Digestive System: Acid regurgitation, anorexia, aphthous stomatitis, cheilitis, cholecystitis, cholestasis, constipation, dry mouth, dyspepsia, eructation, flatulence, gastritis, gingivitis, glossodynia, gingival hemorrhage, increased appetitie, infectious gastroenteritis, jaundice, liver cirrhosis.

Hemic and Lymphatic System: Anemia, lymphadenopathy, spleen disorder.

Metabolic/Nutritional/Immune: Food allergy.

Musculoskeletal System: Arthralgia, back pain, leg pain, myalgia, muscle cramps, muscle weakness, musculoskeletal pain, shoulder pain, stiffness.

Nervous system and Psychiatric: Agitation, anxiety, anxiety disorder, bruxism, decreased mental acuity, depression, dizziness, dream abnormality, dysesthesia, excitement, fasciculation, hypesthesia, nervousness, neuralgia, neurotic disorder, paresthesia, peripheral neuropathy, sleep disorder, somnolence, tremor, vertigo.

Respiratory System: Cough, dyspnea, halitosis, pharyngeal hyperemia, pharyngitis, pneumonia, rales/rhonchi, respiratory failure, sinus disorder, sinusitis, upper respiratory infection.

Skin and Skin Appendage: Body odor, contact dermatitis, dermatitis, dry skin, flushing, folliculitis, herpes simplex, herpes zoster, night sweats, pruritus, seborrhea, skin disorder, skin infection, sweating, urticaria.

Special Senses: Accommodation disorder, blurred vision, eye pain, eye swelling, orbital edema, taste disorder.

Urogenital System: Dysuria, hematuria, hydronephrosis, nocturia, premenstrual syndrome, proteinuria, renal colic, urinary frequency, urinary tract infection, urine abnormality, urine sediment abnormality, urolithiasis.


Sources: Merck and Hoffmann-La Roche package inserts for Crixivan and Invirase .


VIRUSMYTH HOMEPAGE